Classification
Manufacturer
EClass
not containing the term:
Macherey-Nagel 

Silylation reagents - MSTFA

For improved volatility, better thermal stability or low limit of detection in gas chromatography prerequisite: quantitative, rapid and reproducible formation of only on derivative halogen atoms introduced by derivatisation (e.g. trifluoroacetates) allow specific detection (ECD) with the advantage of high sensitivity elution order and fragmentation patterns in MS can be influenced by a specific derivatisation.
Reagents for silylation - alkylation (methylation) - acylation are available.
N-methyl-N-trimethylsilyl-trifluoroacetamide
m.w. 199.1, Bp 70 °C (75 mm Hg), density d20°/4° = 1.11
MSTFA: R' = CF3, R" = CH3
The most volatile trimethylsilyl amide available.
Very strong TMS donor which does not cause any noticeable fouling of the FID burning chamber even after long-time measuring series.
The already good solution characteristics can be improved by addition of submolar quantities of protic solvents (e.g. TFA for extremely polar compounds such as hydrochlorides) or pyridine (e.g. for carbohydrates).
Silylation reagents - MSTFA


Silylation reagents - MSTFA
DescriptionCapacity
ml
PKCat. No.  
MSTFA1207055892
MSTFA1016704091
MSTFA1056085475
MSTFA10016227683
MSTFA5066227450
MSTFA10014001493
MSTFA10014001492
Due to their purpose, derivatisation reagents are very reactive substances. For this reason they should be stored cool and protected from moisture.
The derivatisation reagents are supplied in vials with crimp caps for easy access with a syringe. Vials with pierced sealing disks have limited stability and should be used soon.